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Spontaneous lymphocyte proliferation in severe periodontal disease: role of T and B cells
Author(s) -
Amer A.,
Singh G.,
Darke C.,
Dolby A. E.
Publication year - 1990
Publication title -
journal of oral pathology and medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.887
H-Index - 83
eISSN - 1600-0714
pISSN - 0904-2512
DOI - 10.1111/j.1600-0714.1990.tb00782.x
Subject(s) - immune system , periodontal disease , immunology , lymphocyte , cell growth , disease , t lymphocyte , medicine , biology , pathology , genetics
Spontaneous proliferation of T cells, B cells and unseparated lymphocytes was studied in patients with severe periodontal disease and control subjects. In the patient group only, spontaneous lymphocyte proliferation was reduced, whereas B cell proliferation was enhanced. The findings offer further support for the existence of a disturbance in immune regulation in patients with severe periodontal disease.