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Acinic cell carcinoma of salivary glands: 16 cases with clinicopathologic correlation
Author(s) -
Guimaraes Diva S.,
Amaral Ana P.,
Prado Lygia F.,
Nascimento Antonio G.
Publication year - 1989
Publication title -
journal of oral pathology and medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.887
H-Index - 83
eISSN - 1600-0714
pISSN - 0904-2512
DOI - 10.1111/j.1600-0714.1989.tb01571.x
Subject(s) - acinic cell carcinoma , pleomorphism (cytology) , salivary gland , pathology , grading (engineering) , medicine , carcinoma , mitotic index , mucoepidermoid carcinoma , immunohistochemistry , biology , mitosis , ecology , microbiology and biotechnology
Sixteen cases of acinic cell carcinoma (ACC) of salivary glands were studied and their different clinicopathologic aspects were analysed. ACC occurred more frequently in the 5th and 6th decades of life, and was seen exclusively in major salivary glands. The main complaint of the patients was the presence of a mass, and the majority of the tumors were Stage III and IV when first seen in our institution. The tumors were divided into three histologic grades based on cellular pleomorphism, mitotic activity, and necrosis. This study showed correlation between prognosis and grading. Other important factors in the prognosis were the type of treatment and the duration of symptoms. Surgical resection with free margins is the treatment of choice.