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Ultrastructural findings in clinically uninvolved oral mucosa of patients with HIV infection
Author(s) -
Zhang X.,
Langford A.,
Gelderblom H.,
Reichart P.
Publication year - 1989
Publication title -
journal of oral pathology and medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.887
H-Index - 83
eISSN - 1600-0714
pISSN - 0904-2512
DOI - 10.1111/j.1600-0714.1989.tb00730.x
Subject(s) - oral mucosa , pathology , ultrastructure , human immunodeficiency virus (hiv) , medicine , stage (stratigraphy) , immunopathology , sarcoma , biopsy , viral disease , biology , immunology , paleontology
Twelve biopsies of clinically normal oral mucosa taken from HIV seropositive patients have been investigated by means of light‐ and electron microscopy. Vascular abnormalities were found in all biopsies, regardless of the clinical stage of the HIV infection. In particular slit‐like vascular channels, sparseness of intercellular junctions and swollen, protruded endothelial cells with an increased quantity of Weibel‐Palade bodies were noticed. These findings were similar to those described in lesions of early stage Kaposi's sarcoma.