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Absence of circulating IgG immune complexes in minor recurrent aphthous ulceration
Author(s) -
Bagg J.,
Williams B. D.,
Amos N.,
Dagalis P.,
Walker D. M.
Publication year - 1987
Publication title -
journal of oral pathology and medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.887
H-Index - 83
eISSN - 1600-0714
pISSN - 0904-2512
DOI - 10.1111/j.1600-0714.1987.tb00687.x
Subject(s) - rheumatoid factor , immune system , medicine , immunology , rheumatoid arthritis , antibody , immune complex , immunopathology , gastroenterology
A monoclonal rheumatoid factor binding assay has been employed to detect IgG type immune complexes in sera from 21 patients with minor recurrent aphthous ulceration and 31 control subjects. In only one of the ulcer group patients was there a marginal elevation of immune complexes above the normal range, with no statistically significant difference between the patient and control groups. Assays of intrinsic serum rheumatoid factor and serum IgG, IgM and IgA levels also showed no significant differences between patient and control groups, with all mean values falling within the normal ranges.