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Ultrastructural and histochemical observations on microcalculi in chronic submandibular sialadenitis
Author(s) -
Epivatianos A.,
Harrison J. D.,
Dimitriou T.
Publication year - 1987
Publication title -
journal of oral pathology and medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.887
H-Index - 83
eISSN - 1600-0714
pISSN - 0904-2512
DOI - 10.1111/j.1600-0714.1987.tb00683.x
Subject(s) - ultrastructure , serous fluid , pathology , sialadenitis , submandibular gland , chemistry , anatomy , medicine , salivary gland
A search for microcalculi was made in 14 cases of chronic submandibular sialadenitis. Microcalculi were found in all cases. They were within serous acinar cells and ductal cells, within lumina, and interstitially. They were stained variably by periodic‐acid/Schiff and Alcian Blue at pH 2.5. Ultrastructural analytical examination showed them to consist of crystals containing calcium and phosphorus. The observations support the possibility that microcalculi form in autophagosomes, enter lumina and occasionally become impacted to produce sialolithiasis and sialadenitis.