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Granular cell reaction to surgical glove powder
Author(s) -
Peters E.,
Gardner D. G.,
Altini M.,
Crooks J.
Publication year - 1986
Publication title -
journal of oral pathology and medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.887
H-Index - 83
eISSN - 1600-0714
pISSN - 0904-2512
DOI - 10.1111/j.1600-0714.1986.tb00657.x
Subject(s) - starch , surgical gloves , histiocyte , talc , chemistry , medicine , pathology , surgery , materials science , food science , composite material
The histopathologic features characteristic of the inflammatory response associated with starch powder used as a lubricant for surgical gloves were investigated by implanting starch granules into 3 separate sites on the right side of 8 male Wistar rats. On the opposite side, a sham‐operated site and sites implanted with talc were used as controls. Two rats were killed at 1, 2, 3 & 4‐week intervals and tissue from the implanted sites was assessed for distinctive features. It was found that a consistent feature of the starch‐implanted sites was the presence of large histiocytes containing prominent PAS‐positive, diastase‐resistant inclusions. These cells were not found in the control sites and, thus, were considered characteristic of starch contamination in tissue, even in the absence of identifiable starch granules. A possible clinical case of reaction to starch, identified retrospectively, using these results is discussed.