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Histochemical studies of obstructive adenitis in human submandibular salivary glands. I. Immunohistochemical demonstration of lactoferrin, lysozyme and carcinoembryonic antigen
Author(s) -
Tsukitani K.,
Nakai M.,
Tatemoto Y.,
Hikosaka N.,
Mori M.
Publication year - 1985
Publication title -
journal of oral pathology and medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.887
H-Index - 83
eISSN - 1600-0714
pISSN - 0904-2512
DOI - 10.1111/j.1600-0714.1985.tb00540.x
Subject(s) - carcinoembryonic antigen , immunohistochemistry , pathology , ductal cells , staining , lactoferrin , lysozyme , antigen , submandibular gland , connective tissue , salivary gland , mucin , chemistry , biology , medicine , immunology , cancer , biochemistry
Immunohistochemical detection of lactoforrin (LF), lysozyme (LZ) and carcinoembryonie antigen (CEA) was made in obstructive adenitis of the submandibular glands. Atrophic and altered acinar cells in the early stage of the lesion stained strongly for I.F, whereas they were unreactive or stained slightly for LZ. Ductal cells usually stained for LZ Staining for CEA was strong and irregularly distributed in altered acinar cells. Duct‐like structures and dilated ductal segments in the chronic stage were generally negative for LF LZ and CEA. Secretory components in luminal cavities gave abundant staining for LF. LZ and CEA. Histocytes which infiltrated into the connective tissue in the later stage showed a positive LZ reaction.