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Lichen planus: review and update on pathogenesis
Author(s) -
Scully C.,
ElKom M.
Publication year - 1985
Publication title -
journal of oral pathology and medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.887
H-Index - 83
eISSN - 1600-0714
pISSN - 0904-2512
DOI - 10.1111/j.1600-0714.1985.tb00516.x
Subject(s) - oral lichen planus , etiology , immunology , pathogenesis , antigen , oral tolerance , immune system , medicine , dermatology , pathology
Lichen planus (LP) is a common oral disorder which may represent the manifestation of a mucosal reaction to a variety of aetiological factors. Of the many immunological changes described in LP several may he epiphenomena although a cell‐mediated immune response to unidentified antigens or antigenic changes clearly is involved. Associations with drugs or systemic disorders are well‐defined in some, patients but may, in others, be aleatoric, Finally, the prognosis of oral LP not only differs from that of cutaneous LP but there is little doubt that in a few instances LP is a premalignant condition.