Premium
Studies on the vascular drainage system of the hamster buccal pouch
Author(s) -
Giunta J. L.,
Schwartz J. L.,
Antoniadis D.
Publication year - 1985
Publication title -
journal of oral pathology and medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.887
H-Index - 83
eISSN - 1600-0714
pISSN - 0904-2512
DOI - 10.1111/j.1600-0714.1985.tb00490.x
Subject(s) - cheek pouch , pouch , lymphatic system , medicine , buccal administration , india ink , cheek , hamster , anatomy , pathology , dentistry
Because some investigators feel that the hamster buccal pouch is an immune privileged site with no lymphatic drainage, this study was done to demonstrate and further elucidate a drainage system from the pouch to the cervical nodes. Eight hamsters were injected with india ink, submucosally in the right pouch. Dissections at one or 2 days revealed ink in macrophages in the right submandibular nodes at 2 days. Histologically, the ink was noted within macrophages which aggregated around blood vessels. No lymph vessels were noted in the pouch. Six hamsters were injected with fluorochrome‐labelled latex microspheres. At 2 and at 4 days the microspheres were noted in both the pouches and the ipsilateral submandibular nodes. The results indicate there is a delayed lymphatic drainage from cheek pouches to the submandibular nodes mediated by macrophages.