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Ultrastructural study of intranuclear tubulo‐filaments in a giant cell tumour of bone in a patient with Paget's disease
Author(s) -
ElLabban N. G.
Publication year - 1984
Publication title -
journal of oral pathology and medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.887
H-Index - 83
eISSN - 1600-0714
pISSN - 0904-2512
DOI - 10.1111/j.1600-0714.1984.tb01467.x
Subject(s) - ultrastructure , pathology , paget's disease of bone , disease , giant cell , medicine , anatomy
The intranuclear tubulo‐filaments appearing in giant cells were studied ultrastructurally in a giant cell tumour of bone arising in a patient with Paget's disease. Serial sections have shown the presence of invaginating nuclear membrane around these apparent intranuclear tubulo‐filaments, thus segregating these structures from the nuclear substance proper. Further sectioning showed clear continuity between these tubulo‐filaments and the rest of the cytoplasmic contents. It is found that these apparent intranuclear tubules represent pseudo‐inclusions rather than true intranuclear inclusions.