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Experimental auto‐allergic sialoadenitis in male rats
Author(s) -
Dean D. H.,
Hiramoto R. N.
Publication year - 1984
Publication title -
journal of oral pathology and medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.887
H-Index - 83
eISSN - 1600-0714
pISSN - 0904-2512
DOI - 10.1111/j.1600-0714.1984.tb01401.x
Subject(s) - immunofluorescence , pathogenesis , antibody , pathology , salivary gland , indirect immunofluorescence , submandibular gland , direct fluorescent antibody , medicine , immunohistochemistry , staining , immunology
Induced auto‐allergic lesions in the submandibular glands of rats were studied by immunofluorescence. Direct staining with a goat anti‐rat IgG conjugate was negative. Indirect immunofluorescence revealed a high incidence of anti‐salivary‐duct antibodies in sera from both control and experimental groups. In individual rats, no relationship was found between the presence or absence of serum anti‐salivary antibodies and the presence or absence of salivary auto‐allergic lesions. We conclude that the antibodies demonstrated do not play a role in the pathogenesis of the disease.