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Glucocorticosteroids and oral medicine
Author(s) -
Pedersen A.,
Klausen B.
Publication year - 1984
Publication title -
journal of oral pathology and medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.887
H-Index - 83
eISSN - 1600-0714
pISSN - 0904-2512
DOI - 10.1111/j.1600-0714.1984.tb01395.x
Subject(s) - medicine , rheumatoid arthritis , dermatology , etiology , pemphigus vulgaris , immunology , pathogenesis , disease , erythema multiforme , pemphigus , pathology
The article deals with the use of glucocorticosteroids in the treatment of the oral manifestations of Systemic Lupus Erythematosus (SLE), Disecid Lupus Erythematosus (DLE), Rheumatoid Arthritis (RA) in the temporomandibular joint, Pemphigus Vulgaris , Pemphigoid, Erythema Multiforme Exudativum (EME), Lichen Plaints (LP), and Recurrent Aphthous Ulcerations (RAU). The benefit from steroids is discussed on the basis of current knowledge of etiology and pathogenesis of the various disorders. All of them are characterized by inflammation which appears secondary to a hypersensitivity reaction against autocomponents. Glucocorticoids do not interfere with the primary disease mechanisms. But it is concluded from the literature, that because of anti‐inflammatory and immunosuppressive effects of the hormones, it seems reasonable to profit from steroids as palliatives in acute phases of the diseases and/or as long‐term suppressors of the general host defense.