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Epithelio‐mesenchymal morphology in ameloblastic fibro‐odontoma: a light and electron microscopic study
Author(s) -
Slootweg Pieter J.
Publication year - 1980
Publication title -
journal of oral pathology and medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.887
H-Index - 83
eISSN - 1600-0714
pISSN - 0904-2512
DOI - 10.1111/j.1600-0714.1980.tb01385.x
Subject(s) - odontoblast , mesenchymal stem cell , mesenchyme , ultrastructure , odontogenic tumor , pathology , dentinogenesis , anatomy , chemistry , biology , dentin , odontogenic , medicine
Five cases of ameloblastic fibro‐odontoma were examined by light and electron microscopy. The ultrastructure of the epithelio‐mesenchymal interface was compared with the morphology of the normally developing tooth germ. It was noted that the ultrastructure of the tumors was identical with the normally developing odontogenic tissues up to but not including the differentiation of mesenchymal cells into tall columnar odontoblasts. The absence of odontoblasts in the ameloblastic fibro‐odontomas results in an absence of tubular dentin in place of which a homogeneous collagen‐containing material is synthesized. The failure of mesenchymal cells to acquire the morphology of tall columnar odontoblasts probably is due to the absence of the normally occurring induction of the mesenchyme by the odontogenic epithelium.