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Fine structure of cell types in an ameloblastoma
Author(s) -
Kim S. K.,
Nasjleti C. E.,
Whatherbee L.
Publication year - 1979
Publication title -
journal of oral pathology and medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.887
H-Index - 83
eISSN - 1600-0714
pISSN - 0904-2512
DOI - 10.1111/j.1600-0714.1979.tb01835.x
Subject(s) - connective tissue , stroma , pathology , ultrastructure , epithelium , columnar cell , biology , metaplasia , enamel organ , hepatic stellate cell , anatomy , chemistry , microbiology and biotechnology , ameloblast , enamel paint , medicine , immunohistochemistry , dentistry
. An unusually large and old ameloblastoma, which revealed a diverse histological appearance, was studied by light and electron microscopy. In the tumor, the epithelial component formed several patterns in the collagenous stroma. The epithelial islands, consisting of tall columnar cells surrounding the inner core of stellate cells, mimicked the cells of the inner enamel epithelium and stellate reticulum, respectively, of the normal enamel organ. The ultrastructural appearances of the columnar cells, however, were only similar to those which are seen in undifferentiated preameloblasts. Areas of squamous metaplasia were present, and these squamous cells were structurally similar to the cells al the base of the oral epithelium. Some epithelial cells containing numerous lipid granules and mitochondria formed a network of cords. The connective tissue stroma was made up of fibroblast‐like cells which appear to be metabolically active. In addition, multinucleated giant cells were present in the connective tissue stroma near the epithelial component.