Premium
Lingual carcinogenesis in an inbred strain of hamsters
Author(s) -
Marefat M. P.,
Shklar G.
Publication year - 1978
Publication title -
journal of oral pathology and medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.887
H-Index - 83
eISSN - 1600-0714
pISSN - 0904-2512
DOI - 10.1111/j.1600-0714.1978.tb01883.x
Subject(s) - dmba , inbred strain , strain (injury) , carcinogenesis , tongue , biology , hamster , pathology , anatomy , medicine , genetics , cancer , microbiology and biotechnology , gene
. Epidermoid carcinoma of the lateral border of the tongue can be induced in a standard strain of hamsters, applying DMBA in acetone after traumatizing the area with a root canal broach. Employing the same technique in an inbred strain of hamsters resulted in the more rapid development of carcinomas. The inbred strain should be a useful model for experimental carcinogenesis of tongue.