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Odontoblast metabolism in rats deficient in vitamin D and calcium I
Author(s) -
Engström C.,
Linde A.,
Magnusson B. C.
Publication year - 1977
Publication title -
journal of oral pathology and medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.887
H-Index - 83
eISSN - 1600-0714
pISSN - 0904-2512
DOI - 10.1111/j.1600-0714.1977.tb01801.x
Subject(s) - calcium , vitamin d and neurology , calcium metabolism , metabolism , endocrinology , medicine , vitamin , odontoblast , chemistry , pathology , dentin
. Different rat diets, deficient in calcium and/or vitamin D, were tested for varying experimental periods to obtain changes in serum calcium values, body weight gain and odontoblast‐predentine morphology. One diet, R 25, used during a 14‐day period, was found to induce lowered serum calcium values and an increased predentin width in incisor teeth. Rats fed this diet demonstrated an increase in alkaline phosphatase and ATP‐splitting enzyme activity in dentinogenically active incisor odontoblasts. No other metabolic changes in these cells were demonstrated by the histochemical methods employed.