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Ultrastructure of glycogen‐rich clear cell carcinoma of the palate
Author(s) -
Mohamed Abdel H.
Publication year - 1976
Publication title -
journal of oral pathology and medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.887
H-Index - 83
eISSN - 1600-0714
pISSN - 0904-2512
DOI - 10.1111/j.1600-0714.1976.tb01871.x
Subject(s) - glycogen , ultrastructure , cytoplasm , biology , pathology , epithelium , basement membrane , anatomy , microbiology and biotechnology , medicine , endocrinology
. Tissues from four local recurrences of a palatal tumor and regional lymph node metastases were studied by light microscopy while ultrastructural observations were made on the most recent tumor. The tumor was composed of solid sheets, clumps, and small nests of polyhedral epithelial cells with well‐defined cell boundaries, clear cytoplasm, and cellular pleomorphism. Histochemical stains indicated the presence of abundant intracellular glycogen deposits in all tumor specimens examined. Ultrastructural observations revealed solid sheets of epithelial cells which lacked both surrounding basement lamina and ductal arrangements. The cytoplasm of the tumor cells was filled with P glycogen deposits and contained scattered bundles of tonofilaments and scant organelles. The transition between the glycogen‐rich tumor cells and surface epithelium showed intervening cells which contained diffusely dispersed ribosomes and small amounts of glycogen. The tumor probably originated from surface epithelium.