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Electron microscopic observations of “keratin pools” in chronic hyperplastic oral mucosa
Author(s) -
Archard H. O.,
Denys F. R.,
Martinez M. G.
Publication year - 1976
Publication title -
journal of oral pathology and medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.887
H-Index - 83
eISSN - 1600-0714
pISSN - 0904-2512
DOI - 10.1111/j.1600-0714.1976.tb01788.x
Subject(s) - keratin , oral mucosa , electron microscope , extracellular , pathology , epithelium , chemistry , cytoplasm , ultrastructure , biology , biophysics , medicine , physics , optics , biochemistry
. “Keratin pools,” previously characterized clinically and histochemically in the superficial epithelium of chronic hyperplastic oral mucosa, were studied by light and electron microscopy. These occured as small beaded and larger coalescent masses which varied in metachromasia. Ultrastructurally, the “keratin pools” consisted of electron‐dense, amorphous or finely‐granular material developing and coalescing, chiefly as extracellular deposits. The “pools” frequently possessed a layered arrangement alternating with cells having distinct tonofilaments, desmosomes, and definite cell membranes. Occasional bands of filamentous‐like material, possibly representing tonofilament bundles, were observed in some “pools.”