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Changes in granular endoplasmic reticulum induced in cultured human monocytes by colony stimulating factor
Author(s) -
Mohammad Abdel Rahim
Publication year - 1976
Publication title -
journal of oral pathology and medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.887
H-Index - 83
eISSN - 1600-0714
pISSN - 0904-2512
DOI - 10.1111/j.1600-0714.1976.tb01761.x
Subject(s) - endoplasmic reticulum , microbiology and biotechnology , biology , chemistry , immunology
. The supernatant portion of cultured human monocytes produces a biological factor known as colony stimulating factor. The addition of culture fluid containing colony stimulating factor to cultured human monocytes produced morphologic changes in the granular endoplasmic reticulum. Granular endoplasmic reticulum changed its appearance from long slender cisternae to a concentric pattern (whorls) averaging seven rows per structure 120 min following the addition of culture fluids containing colony stimulating factor.