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In vivo calcification of implanted bone cells
Author(s) -
Mckinney Ralph V.,
Dirksen Thomas R.,
Schuster George S.,
Bustos Sergio
Publication year - 1974
Publication title -
journal of oral pathology and medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.887
H-Index - 83
eISSN - 1600-0714
pISSN - 0904-2512
DOI - 10.1111/j.1600-0714.1974.tb01718.x
Subject(s) - calvaria , calcification , in vivo , anatomy , pathology , chemistry , matrix (chemical analysis) , bone cell , in vitro , medicine , biology , microbiology and biotechnology , biochemistry , chromatography
. Bone cells raised in cell culture from the osteogenic cells of newborn rat calvaria were reimplanted in the same species of animals from which the cells were derived. The cells were sealed in Teflon rings containing Millipore filters over both ends. Evidence of calcification occurred inside the implanted ring chambers at 118 and 279 days following implantation in vivo. The calcified matrix produced by the cells had a pattern reminiscent of membranous bone production.