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Parameters of haematology, clinical chemistry and lipid metabolism in the common marmoset and alterations under stress conditions
Author(s) -
Kuehnel F.,
Grohmann J.,
Buchwald U.,
Koeller G.,
Teupser D.,
Einspanier A.
Publication year - 2012
Publication title -
journal of medical primatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.31
H-Index - 42
eISSN - 1600-0684
pISSN - 0047-2565
DOI - 10.1111/j.1600-0684.2012.00550.x
Subject(s) - mean corpuscular volume , marmoset , physiology , hematology , medicine , pathological , endocrinology , biology , hematocrit , ecology
Common marmosets are suitable non‐human primate models for many human diseases. Standard values for blood parameters are required to evaluate physiological and pathological situations. Two studies were conducted: study I to determine standard values and study II to examine these under changed housing conditions. In study I, all parameters for clinical chemistry were similar in range for both genders with these specifics: male marmosets had significantly higher total and LDL cholesterol levels than females, whereas the mean corpuscular volume and the mean corpuscular haemoglobin were significantly lower than in females. In study II, glucose, lymphocytes and salivary cortisol were significantly lower, and faecal cortisol was increased during the change of housing conditions. In conclusion, standard values for haematology and clinical chemistry for the common marmoset were determined. Further on, parameters that are influenced by relocation stress and its importance for experimental results are described.