Androgen receptor CAG repeat polymorphism in males of six non‐human primate species | Zendy

Mubiru James N. | Zendy; Cavazos Nicole | Zendy; Hemmat Peggah | Zendy; GarciaForey Magdalena | Zendy; Shade Robert E. | Zendy; Rogers Jeffrey | Zendy

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Androgen receptor CAG repeat polymorphism in males of six non‐human primate species

Author(s) -

Mubiru James N.,

Cavazos Nicole,

Hemmat Peggah,

GarciaForey Magdalena,

Shade Robert E.,

Rogers Jeffrey

Publication year - 2012

Publication title -

journal of medical primatology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.31

H-Index - 42

eISSN - 1600-0684

pISSN - 0047-2565

DOI - 10.1111/j.1600-0684.2011.00517.x

Subject(s) - microsatellite , biology , primate , androgen receptor , polymorphism (computer science) , genetics , androgen , nonhuman primate , zoology , genotype , evolutionary biology , allele , endocrinology , gene , ecology , hormone , prostate cancer , cancer

Background Androgen receptor [CAG] n microsatellite has been linked to human diseases. Methods Six non‐human primates were genotyped for the [CAG] n microsatellite. Results Marmosets and macaques are monomorphic, while mangabeys, baboons, and chimpanzees are polymorphic. Conclusions Non‐human primates that are polymorphic for the microsatellite are candidate animal models for CAG‐related diseases.

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