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Transurethral bladder catheterization of male rhesus macaques: a refinement of approach
Author(s) -
Wickham L. Alexandra,
Kulick Alison A.,
Gichuru Loise,
Donnelly Marcie J.,
Gai Cesaire L.,
Johnson Christopher V.,
Hickey Emily J.,
Nagabukuro Hiroshi
Publication year - 2011
Publication title -
journal of medical primatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.31
H-Index - 42
eISSN - 1600-0684
pISSN - 0047-2565
DOI - 10.1111/j.1600-0684.2011.00494.x
Subject(s) - medicine , sedation , catheter , complication , urethra , urinary bladder , lumen (anatomy) , urinary catheterization , surgery , anesthesia , urology
Background Successful transurethral bladder catheterization in male non‐human primates can be challenging. An optimized approach for consistent and reproducible catheterization using a refined technique is described. Methods Under sedated and non‐sedated conditions, transurethral bladder catheterization was performed on 25 male rhesus macaques of varying ages and body weights over time. A refined technique ensuring optimal lubrication of the urethral canal prior to catheter insertion was utilized along with various single and multiple lumen catheters. Results All animals were successfully catheterized. Sixty‐five catheterization sessions were conducted with a high overall success rate (100%). The incidence of catheter (10%) and post‐catheterization (2%) complications was low. Conclusions The urinary bladder of male rhesus can be reliably and reproducibly catheterized with minimal complication using this approach. Successful catheterization was facilitated by thorough urethral lubrication and using suitable catheters. In addition, this approach may be performed without sedation on thoroughly conditioned animals.