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High‐risk pregnancy in rhesus monkeys ( Macaca mulatta ): a case of ectopic, abdominal pregnancy with birth of a live, term infant, and a case of gestational diabetes complicated by pre‐eclampsia
Author(s) -
KrugnerHigby Lisa,
Luck Melissa,
Hartley Deborah,
Crispen Heather M.,
Lubach Gabriele R.,
Coe Christopher L.
Publication year - 2009
Publication title -
journal of medical primatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.31
H-Index - 42
eISSN - 1600-0684
pISSN - 0047-2565
DOI - 10.1111/j.1600-0684.2009.00349.x
Subject(s) - pregnancy , medicine , abdominal pregnancy , gestation , obstetrics , abdomen , gestational diabetes , ectopic pregnancy , gynecology , surgery , biology , genetics
Background Cases of abdominal pregnancy, in the form of intra‐abdominal mummified fetuses, have been described in nonhuman primates. Gestational diabetes and pre‐eclampsia are common pregnancy complications in women. Methods Two timed‐bred rhesus monkeys had high‐risk pregnancies, an abdominal pregnancy with delivery of a live term infant, and a case of gestational diabetes that later developed pre‐eclampsia. Results The monkey that had abdominal pregnancy later died from septic peritonitis. The monkey had a colonic adenocarcinoma that may have allowed leakage of intestinal contents into the abdomen. Her infant was fostered to another female and survived. The monkey with gestational diabetes and pre‐eclampsia was treated with a regimen similar to that used in women, and a live infant was delivered at day 157 of gestation by Caesarian section. Conclusion These cases underscore the value of timed‐breeding and the similarities between pregnancy complications in women and in nonhuman primates.