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A novel alternative placement site and technique for totally implantable vascular access ports in non‐human primates
Author(s) -
Graham Melanie L.,
Rieke Eric F.,
Dunning Michele,
Mutch Lucas A.,
Craig Angela M.,
Zolondek Elizabeth K.,
Hering Bernhard J.,
Schuurman HenkJan,
Bianco Richard W.
Publication year - 2009
Publication title -
journal of medical primatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.31
H-Index - 42
eISSN - 1600-0684
pISSN - 0047-2565
DOI - 10.1111/j.1600-0684.2009.00340.x
Subject(s) - medicine , vein , vascular access , surgery , saphenous veins , port (circuit theory) , cephalic vein , catheter , venous access , great saphenous vein , hemodialysis , electrical engineering , engineering
Background Two novel approaches to implanting a central venous catheter port in non‐human primates (NHPs) using peripheral insertion are presented and compared. Methods Sixty vascular access port (VAP) implants were attempted in 52 NHPs by saphenous vein puncture (n = 20) or saphenous vein cutdown (n = 40). Results Fifty eight procedures were successful. Eighteen of 20 VAPs were successfully placed using saphenous vein puncture, and 40 of 40 using saphenous vein cutdown. There were no significant differences between procedures. Mean implantation times were similar between groups. At explant or study endpoint, all 58 VAPs were patent. Conclusions Vascular access port implantation by saphenous vein puncture or saphenous vein cutdown is safe and effective in NHPs. It is less invasive than conventional procedures, has fewer complications, provides outstanding patency, and reduces surgery time. Furthermore, it allows for cooperative in‐homecage VAP use, minimizing handling stress. We recommend these refined methods for long‐term vascular access in NHPs.