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Stillbirths in Macaca fascicularis
Author(s) -
Sesbuppha Wacharaporn,
Chantip Surachai,
Dick Edward J.,
SchlabritzLoutsevitch Natalia E.,
GuardadoMendoza Rodolfo,
Butler Stephanie D.,
Frost Patrice A.,
Hubbard Gene B.
Publication year - 2008
Publication title -
journal of medical primatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.31
H-Index - 42
eISSN - 1600-0684
pISSN - 0047-2565
DOI - 10.1111/j.1600-0684.2007.00275.x
Subject(s) - etiology , placental abruption , medicine , incidence (geometry) , obstetrics , fetus , pregnancy , fetal death , pneumonia , perinatal mortality , gynecology , biology , pathology , physics , optics , genetics
Background Stillbirths in non‐human primates are a major problem and represent failure of the maternal–fetal–placental unit to maintain normal relationships because of various endogenous, undetermined or environmental factors. Methods Records of 236 stillborns and their dams in a Macaca fascicularis colony during a 7‐year period were reviewed retrospectively. Results The 7‐year stillbirth incidence was 11.99% (236 stillbirths, 1967 live births). Most (61.02%, n = 144) were of undetermined etiology. Fetal causes included trauma (22.46%, n = 53), fetal pneumonia (0.85%, n = 2) and congenital anomalies (0.42%, n = 1). Maternal causes included dystocia (9.75%, n = 23) and uterine rupture (0.42%, n = 1). Forty‐nine placentas were available for histologic evaluation; there was placentitis in five, necrosis in five and placental abruption in two. Most stillbirths occurred close to term. First stillbirths usually occurred in 8‐ to 12‐year‐old animals during the first six pregnancies. Conclusions Most stillbirths were of undetermined etiology. Fetal trauma was the most common cause.