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Dermatitis in a rhesus macaque ( Macaca mulatta ) experimentally infected with simian immunodeficiency virus
Author(s) -
Wilk Jennifer,
Lewis Anne,
Lukas Victor
Publication year - 2008
Publication title -
journal of medical primatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.31
H-Index - 42
eISSN - 1600-0684
pISSN - 0047-2565
DOI - 10.1111/j.1600-0684.2007.00255.x
Subject(s) - simian immunodeficiency virus , macaque , immunodeficiency , immunology , virology , rhesus macaque , etiology , antibiotics , virus , medicine , trimethoprim , dermatology , biology , microbiology and biotechnology , pathology , immune system , paleontology
Dermatopathies are common with human immunodeficiency virus (HIV) infection, affecting an estimated 90% of HIV patients. Opportunistic infections are common and include viral, bacterial and fungal etiologies. Dermal eruptions from highly active anti‐retroviral therapy (HAART) or antibiotics such as trimethoprim‐sulfamethoxazole (TMS) are also common, and can be challenging to differentiate from other causes of dermatitis. Presented is a challenging dermatology case involving a six year old male rhesus macaque experimentally infected with simian immunodeficiency virus (SIV). Skin cultures identified multi‐antibiotic resistant Staphylococcus aureus , with incomplete resolution following appropriate antibiotic treatment. Skin biopsy results indicated non‐specific dermatitis not consistent with typical SIV dermatitis and with a hypersensitivity component. Fungal culture revealed aspergillosis, and the patient responded favorably to oral itraconazole therapy.