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Antibody responses to two encephalomyocarditis virus vaccines in rhesus macaques ( Macaca mulatta )
Author(s) -
Emerson Carol L.,
Wagner Joseph L.
Publication year - 1996
Publication title -
journal of medical primatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.31
H-Index - 42
eISSN - 1600-0684
pISSN - 0047-2565
DOI - 10.1111/j.1600-0684.1996.tb00191.x
Subject(s) - virology , antibody , virus , biology , antibody response , immunology
Two groups of rhesus macaques ( Macaca mulatta ) housed in rodent‐controlled outdoor corrals were inoculated with two different encephalomyocarditis virus (EMCV) vaccines. One group (n = 45) received a vaccine made from an inactivated field isolate of virus cultured during an outbreak at a zoo in Florida. This vaccine produced fourfold increases in the titers of 28 animals (62%); the increases persisted for at least 18 months (last test) after a single injection of the vaccine. The other group (n = 51) received a vaccine made from an inactivated porcine field strain of the virus. This vaccine did not produce titers in any of the vaccinees.