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Isolation and characterization of the first simian immunodeficiency virus from a feral sooty mangabey ( Cercocebus atys ) in West Africa
Author(s) -
Chen Zhiwei,
Telfer Paul,
Reed Patricia,
Zhang Linqi,
Getti Agegnehu,
Ho David D.,
Marx Preston A.
Publication year - 1995
Publication title -
journal of medical primatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.31
H-Index - 42
eISSN - 1600-0684
pISSN - 0047-2565
DOI - 10.1111/j.1600-0684.1995.tb00155.x
Subject(s) - simian immunodeficiency virus , biology , virology , simian , lineage (genetic) , serology , virus , isolation (microbiology) , zoology , genetics , antibody , gene , microbiology and biotechnology
The lineage of HIV‐2‐like viruses was studied in feral sooty mangabeys (SMs) by serological and genetic methods. Four feral sooty mangabeys were positive for simian immunodeficiency virus (SIV) antibodies and a new isolate, SIV smSL92a , was obtained. Genetic analysis of gag genes showed that SIV smSL92a was highly diverse and a distinct sequence subtype within the SIV sm /HIV‐2 family. The results showed that SIV sm is the most diverse group of SIVs found thus far in a single monkey species.