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Individualized gonadotropin regimens for follicular stimulation in macaques during in vitro fertilization (IVF) cycles
Author(s) -
ZelinskiWooten Mary B.,
Alexander Manfred,
Christensen Cynthia L.,
Wolf Don P.,
Hess David L.,
Stouffer Richard L.
Publication year - 1994
Publication title -
journal of medical primatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.31
H-Index - 42
eISSN - 1600-0684
pISSN - 0047-2565
DOI - 10.1111/j.1600-0684.1994.tb00122.x
Subject(s) - follicular phase , gonadotropin , gamete , luteal phase , in vitro fertilisation , oocyte , follicle , stimulation , medicine , andrology , biology , human fertilization , endocrinology , pregnancy , embryo , hormone , anatomy , genetics , microbiology and biotechnology
Follicular stimulation was compared in macaques receiving sequential gonadotropin treatment which was terminated after seven, eight, or nine days depending on the time required to attain preselected criteria of follicular maturation. Although estradiol levels and follicle sizes varied, the number of follicles and oocytes/animal, oocyte nuclear maturity, IVF rates and progesterone levels during the luteal phase were similar among groups. Reducing the duration of gonadotropin treatment to individualize follicular stimulation regimens does not compromise follicle or gamete quality.