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Spermatogenesis and hormone levels in rhesus macaques inoculated with simian immunodeficiency virus
Author(s) -
Nadler Ronald D.,
Manocha Atul D.,
McClure Harold M.
Publication year - 1993
Publication title -
journal of medical primatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.31
H-Index - 42
eISSN - 1600-0684
pISSN - 0047-2565
DOI - 10.1111/j.1600-0684.1993.tb00679.x
Subject(s) - simian immunodeficiency virus , biology , azoospermia , simian , virology , virus , cachexia , testosterone (patch) , immunodeficiency , immunology , endocrinology , infertility , pregnancy , immune system , genetics , cancer
The presence of sperm in testicular tissue of rhesus macaques that died as a result of infection with simian immunodeficiency virus (SIV) was related to age and body weight. Depressed testosterone levels were not associated with elevated LH levels. The data suggest that azoospermia in the SIV‐infected macaques was due to cachexia and not a direct effect of virus on the testis, supporting a similar hypothesis regarding azoospermia in men infected with human immunodeficiency virus.