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Immunohistochemical distribution of leucocyte antigens in lymphoid tissues of cynomolgus monkeys ( Macaca fascicularis )
Author(s) -
Li SuLing,
Kaaya Ephata,
Feichtinger Hans,
Biberfeld Gunnel,
Biberfeld Peter
Publication year - 1993
Publication title -
journal of medical primatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.31
H-Index - 42
eISSN - 1600-0684
pISSN - 0047-2565
DOI - 10.1111/j.1600-0684.1993.tb00673.x
Subject(s) - immunohistochemistry , antigen , immunostaining , lymphatic system , lymph node , pathology , biology , antibody , immunology , microbiology and biotechnology , medicine
Crossreactivity of antibodies to human leucocyte antigens with lymphoid tissues of cynomolgus monkeys was studied by immunohistochemistry and immunoblotting. Of a total of 54 clusters of differentiation (CD) antigens, 39 were expressed essentially with the same immunostaining patterns in the monkey as in human lymphoid tissues. By immunoblotting L26 (CD20) detected a 35 Kd molecule in the monkey lymph node. Our observations indicated that most of the CD antigens are expressed and can be studied in lymphoid tissues of cynomolgus monkeys.