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Cytotoxic T lymphocyte epitopes shared between HIV‐1, HIV‐2, and SIV
Author(s) -
Gotch Frances,
Nixon Douglas,
Gallimore Awen,
McAdam Stephen,
McMichael Andrew
Publication year - 1993
Publication title -
journal of medical primatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.31
H-Index - 42
eISSN - 1600-0684
pISSN - 0047-2565
DOI - 10.1111/j.1600-0684.1993.tb00649.x
Subject(s) - epitope , macaque , simian immunodeficiency virus , virology , cytotoxic t cell , rhesus macaque , peptide , human immunodeficiency virus (hiv) , human leukocyte antigen , immunology , biology , major histocompatibility complex , peptide vaccine , t lymphocyte , immune system , antigen , in vitro , genetics , biochemistry , paleontology
A peptide epitope from the gag protein of SIV and from HIV‐1 is described which is presented by a cynomolgus macaque MHC molecule and with HLA B14. Comparisons were drawn between recognition of this peptide and that of a second peptide defined in SIV and HIV‐2 which has been reported to be presented by the rhesus macaque molecule MaMuA01 and HLA B53 respectively.