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Determination of the time of ovulation in chimpanzees by measurement of LH, estrone sulfate, and pregnanediol 3α‐glucuronide in urine: Comparison with serum hormone patterns
Author(s) -
Steinetz Bernard G.,
Ducrot Cecile,
Randolph Carla,
Mahoney C. James
Publication year - 1992
Publication title -
journal of medical primatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.31
H-Index - 42
eISSN - 1600-0684
pISSN - 0047-2565
DOI - 10.1111/j.1600-0684.1992.tb00585.x
Subject(s) - pregnanediol , ovulation , urine , estrone , endocrinology , medicine , estrone sulfate , radioimmunoassay , luteinizing hormone , menstrual cycle , chemistry , hormone , menstruation
The concentrations of LH, total estrogens, and pregnanediol 3α‐glucuronide (PdG) were determined by specific radioimmunoassays on daily overnight urine samples obtained in 13 menstrual cycles of six adult female chimpanzees during the periods of increasing, maximal, and decreasing tumescence of the perineal sex skin. The peaks of estrogens and LH and the rise in PdG in urine accurately rellected the peaks of estradiol‐17β and LH and the subsequent rise in progesterone in the serum of the same animals during the same menstrual cycles, and can be used to predict and verify the occurrence of ovulation, thus avoiding the repeated tranquilizations necessary to obtain daily blood samples.