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Anti‐human red cell monoclonal antibodies produced by macaque‐mouse heterohybridomas
Author(s) -
Blancher A.,
Socha W.W.
Publication year - 1991
Publication title -
journal of medical primatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.31
H-Index - 42
eISSN - 1600-0684
pISSN - 0047-2565
DOI - 10.1111/j.1600-0684.1991.tb00549.x
Subject(s) - monoclonal antibody , macaque , rhesus macaque , virology , antibody , biology , microbiology and biotechnology , immunology , neuroscience
Eight monoclonal antibodies (Mabs) against human red cells were produced by macaque‐mouse heterohybridomas. All Mabs uniformly reacted with all human red blood cells tested, but only some agglutinated the red cells of anthropoid apes occasionally detecting intraspecies polymorphisms. None was reactive with blood of Old and New World monkeys. One of the Mabs recognized the V c antigen of the chimpanzee V‐A‐B‐D system, the homologue of the human M‐N blood group system.