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Siderophilic bodies associated with hemosiderosis and atypical mycobacterial infection in an island siamang ( Hylobates syndactylus )
Author(s) -
Munson Linda,
Luibel Francis J.,
Van Kruiningen Herbert J.
Publication year - 1991
Publication title -
journal of medical primatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.31
H-Index - 42
eISSN - 1600-0684
pISSN - 0047-2565
DOI - 10.1111/j.1600-0684.1991.tb00532.x
Subject(s) - hylobates , hemosiderosis , biology , zoology , medicine , microbiology and biotechnology , pathology
Laminated iron concretions were noted in the liver of an aged siamang ( Hylobates syndactylus ) that had granulomatous enteritis and hepatitis due to Mycobacterium avium intracellulare infection. Preexisting hepatic siderosis, iron sequestration in macrophages, and compromised macrophage function due to mycobacterial infection are proposed as the basis for the abundance and size of the concretions. Similar siderophilic bodies and concomitant siderosis occurred in other siamangs. The concretions are similar to Schumann bodies and Michaelis‐Gutmann bodies associated with granulomatous disease in other species.