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The use of a urinary estrone conjugates assay for detection of optimal mating time in the cynomolgus macaque ( Macaca fascicularis )
Author(s) -
Behboodi Esmail,
Katz David F.,
Samuels Steven J.,
Tell Lisa,
Hendrickx Andrew G.,
Lasley Bill L.
Publication year - 1991
Publication title -
journal of medical primatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.31
H-Index - 42
eISSN - 1600-0684
pISSN - 0047-2565
DOI - 10.1111/j.1600-0684.1991.tb00525.x
Subject(s) - morning , estrone , ovulation , macaque , medicine , biology , endocrinology , urinary system , menstrual cycle , physiology , zoology , estrogen , ecology , hormone
Forty‐four female cynomolgus macaques ( Macaca fascicularis ) were examined to determine the optimum fertile period for mating. Daily urinary estrone conjugates (E 1 C) were measured, beginning on day 7 of the menstrual cycle, until a 1.5‐gold E 1 C rise above the baseline was detected. The females were bred the next morning. Pregnancies were verified in all animals at day 18 postbreeding, and/or on day 25 postbreeding. Serum progesterone levels were used to correlate the relationship between ovulation and the E 1 C peak. Forty‐four of the 57 cycles indicated a urinary E 1 C peak between days 10–15 of the menstrual cycle; this peak occurred on the day following the initial 1.5‐fold to twofold rise in 90% of the cycles. A single 2‐hr mating period the day before, the day of, or the day after the E 1 C peak resulted in conception in 17 of 44 (38.6%) animals.