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Maternal transmission of SIV smm in rhesus macaques
Author(s) -
McClure Harold M.,
Anderson Daniel C.,
Fultz Patricia N.,
Ansari Aftab A.,
JehudaCohen Tamar,
Villinger Francois,
Klumpp Sherry A.,
Switzer William,
Lockwood Ellen,
Brodie Anne,
Keyserling Harry
Publication year - 1991
Publication title -
journal of medical primatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.31
H-Index - 42
eISSN - 1600-0684
pISSN - 0047-2565
DOI - 10.1111/j.1600-0684.1991.tb00516.x
Subject(s) - transmission (telecommunications) , virus , breast milk , biology , simian immunodeficiency virus , virology , medicine , obstetrics , biochemistry , electrical engineering , engineering
Fifteen SIV‐infected rhesus monkeys delivered 13 livebirths and two stillbirths; one livebirth died at three days of age. While all infants were culture‐negative for SIV at birth, nine had maternal antibodies that disappeared by six months of age. Three infants subsequently seroconverted and became virus positive at 9–15 months. Milk samples from all mothers were virus‐negative at parturition but samples from four animals were virus‐positive at nine and 12 months. This study documents maternal transmission of SIV and suggests transmission by breast‐feeding.