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SIV of stump‐tailed macaque (SIV stm ) is a divergent Asian isolate
Author(s) -
Khan Arifa S.,
Galvin Teresa A.,
Jennings Myra B.,
Gardner Murray B.,
Lowenstine Linda J.
Publication year - 1991
Publication title -
journal of medical primatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.31
H-Index - 42
eISSN - 1600-0684
pISSN - 0047-2565
DOI - 10.1111/j.1600-0684.1991.tb00513.x
Subject(s) - macaque , macaca nemestrina , rhesus macaque , biology , simian immunodeficiency virus , virology , genetics , sequence analysis , sequence (biology) , human immunodeficiency virus (hiv) , gene , paleontology
Analysis of molecularly cloned DNAs of SIVs isolated from Asian rhesus macaque ( Macaca mulatta ; SIV mac ) and pig‐tailed macaque ( Macaca nemestrina ; SIV mne ) has indicated a high degree of sequence homology between these viruses. Thus SIV mac and SIV mne might have originated from the same or very closely related viruses. We have cloned and sequenced a PCR‐amplified segment containing the LTR sequences of SIV originating from a stump‐tailed macaque ( Macaca arctoides ; SIV stm ). Comparative sequence analysis indicates that SIV stm belongs to the SIV/HIV‐2 group; however, it is genetically distinct from the other members.