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Presence of antibody to Cyno‐EBV in domestically bred cynomolgus monkeys (Macaca fascicularis)
Author(s) -
Fujimoto Koji,
Honjo Shigeo
Publication year - 1991
Publication title -
journal of medical primatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.31
H-Index - 42
eISSN - 1600-0684
pISSN - 0047-2565
DOI - 10.1111/j.1600-0684.1991.tb00489.x
Subject(s) - antibody , biology , antibody titer , japanese monkeys , titer , virology , virus , primate , immunology , zoology , neuroscience
The presence of an antibody to the Cyno‐EBV was studied with Cyno‐EBV bearing cell line (Ts‐B‐9) as antigen in 186 domestically bred cynomolgus monkeys ( Macaca fascicularis) ranging in age from birth to 18 yr as well as in 20 adult (older than 10 yr) cynomolgus monkeys of wild origin. The maternal antibody to Cyno‐EBV persisted for less than four mo after birth in infant monkeys. After one yr of age, all the domestically bred monkeys were consistently positive for Cyno‐EBV. In the monkeys of wild origin also, the anti‐Cyno‐EBV antibody was detected without exception. Antibody titers in adult monkeys varied from 1:80 to 1:640.