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Studies With Human, Baboon, and Vervet Monkey Chorionic Gonadotrophins
Author(s) -
Mwenda J.M.,
Bambra C.S.,
Tarara R.P.
Publication year - 1990
Publication title -
journal of medical primatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.31
H-Index - 42
eISSN - 1600-0684
pISSN - 0047-2565
DOI - 10.1111/j.1600-0684.1990.tb00476.x
Subject(s) - baboon , vervet monkey , isoelectric focusing , bioassay , chromatography , immunoassay , endocrinology , isoelectric point , biology , chemistry , medicine , biochemistry , antibody , zoology , immunology , genetics , enzyme
Vervet monkey, baboon, and human chorionic gonadotrophin(CG) were partially purified and their activity was monitored using radioimmuno‐ and radioreceptor‐assays. They showed similar behaviour during ion exchange chromatography and isoelectric focusing and had isoelectric points between pH 4.50 and 5.13, The Stokes' radii were 32Å, 34Å, and 33Å for vervet monkey, baboon, and human CG, respectively. Corresponding immunoassay potencies were 476.9, 1,143.1, and 9,600 IU/mg, while the bioassay estimates were 491.7, 997.8, and 8,950.0 IU/mg.