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Experimental Infection of African Green Monkeys and Cynomolgus Monkeys With a SIV AGM Strain Isolated From a Healthy African Green Monkey
Author(s) -
Honjo Shigeo,
Narita Toyoko,
Kobayashi Rieko,
Hiyaoka Akio,
Fujimoto Koji,
Takasaka Masao,
Sakakibara Ippei,
Mukai Ryozaburo,
Ishikawa Koichi,
Ohta Yoshihiro,
Hayami Masanori
Publication year - 1990
Publication title -
journal of medical primatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.31
H-Index - 42
eISSN - 1600-0684
pISSN - 0047-2565
DOI - 10.1111/j.1600-0684.1990.tb00249.x
Subject(s) - african green monkey , simian immunodeficiency virus , primate , virology , virus , inoculation , biology , old world , antibody , isolation (microbiology) , host (biology) , strain (injury) , immunology , microbiology and biotechnology , zoology , anatomy , neuroscience , ecology
An infection occurred in all African green monkeys and cynomolgus monkeys experimentally inoculated with SIV AGM [TYO‐1], as demonstrated by the appearance of an antibody to SIV AGM [TYO‐1] and the isolation of the virus. No monkey exhibited overt clinical disorders throughout the experimental period of 42 weeks. Thus, SIV AGM was not pathogenic to its original host or to macaques, This system is proposed as a model for HIV infection manifesting no overt disease.