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Appropriate Conditions for Maintenance of Chimpanzees in Studies With Blood‐Borne Viruses: An Epidemiologic and Psychosocial Perspective
Author(s) -
Prince Alfred M.,
Goodall Jane,
Brotman Betsy,
Dienske Herman,
Schellekens Huub,
Eichberg Jorg W.
Publication year - 1989
Publication title -
journal of medical primatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.31
H-Index - 42
eISSN - 1600-0684
pISSN - 0047-2565
DOI - 10.1111/j.1600-0684.1989.tb00202.x
Subject(s) - psychosocial , hepatitis b virus , isolation (microbiology) , human immunodeficiency virus (hiv) , hepatitis b , epidemiology , virology , hepatitis virus , virus , virus isolation , medicine , immunology , perspective (graphical) , biology , psychiatry , bioinformatics , artificial intelligence , computer science
Based on the known epidemiology of the viruses that account for the bulk of the need for chimpanzees in biomedical research—hepatitis B virus (HBV), non‐A, non‐B (NANB) hepatitis virus, and human immunodeficiency virus (HIV)—as well as the psychosocial needs of this species, requirements for appropriate isolation conditions for these animals have been reviewed. We believe that animals should generally be housed in groups of at least two in the same cage, and that cages encased in solid‐walled isolator boxes for housing of single chimpanzees are unnecessary for virologically adequate isolation for studies of HBV, NANB and HIV, and cause sensory and psychosocial deprivation, which contravenes their psychological well‐being.