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Cardiac Allotransplantation Across Major Blood Group Barriers in the Baboon
Author(s) -
Cooper D.K.C.,
Lexer G.,
Rose A.G.,
Keraan M.,
Rees J.,
Du Toit E.,
Oriol R.
Publication year - 1988
Publication title -
journal of medical primatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.31
H-Index - 42
eISSN - 1600-0684
pISSN - 0047-2565
DOI - 10.1111/j.1600-0684.1988.tb00197.x
Subject(s) - allotransplantation , abo blood group system , baboon , medicine , transplantation , biology
In heterotopic heart transplantation experiments in Chacma baboons, some of the animals were significantly immunosuppressed with cyclosporine, resulting in prolonged cardiac allograft survival. ABO blood group incompatibility between recipient and donor did not significantly influence mean allograft survival, but early hyperacute (vascular) or acute (cellular) rejection occurred only when ABO incompatibility was present.