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Serum Concentrations of Vitamin D Metabolites in Cayo Santiago Rhesus Macaques
Author(s) -
Vieth Reinhold,
Kessler Matt J.,
Pritzker Kenneth P.H.
Publication year - 1987
Publication title -
journal of medical primatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.31
H-Index - 42
eISSN - 1600-0684
pISSN - 0047-2565
DOI - 10.1111/j.1600-0684.1987.tb00345.x
Subject(s) - vitamin d and neurology , metabolite , medicine , endocrinology , rhesus macaque , hormone , calcifediol , vitamin , cholecalciferol , vitamin d deficiency , biology , chemistry , physiology , immunology
Serum 25‐hydroxyvitamin D (25[OH]D), an index of vitamin D nutrition, and the calcium‐regulating hormone 1,25‐dihydroxyvitamin D (1,25[OH] 2 D) were measured in rhesus macaques of various ages. Both metabolites were much higher in monkeys than in man. For 25(OH)D there was no sex difference, and this metabolite increased with age (P > 0.05). The 1,25(OH) 2 D fell with age for males (P < 0.02), but not for females. Pregnant or lactating females had significantly elevated 1,25(OH) 2 D levels (P < 0.025).