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Lack of Transmission of Human Immunodeficiency Virus From Infected to Uninfected Chimpanzees
Author(s) -
Fultz Patricia N.,
Greene Cornelia,
Switzer William,
Swenson Brent,
Anderson Daniel,
McCIure Harold M.
Publication year - 1987
Publication title -
journal of medical primatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.31
H-Index - 42
eISSN - 1600-0684
pISSN - 0047-2565
DOI - 10.1111/j.1600-0684.1987.tb00344.x
Subject(s) - transmission (telecommunications) , virology , biology , virus , peripheral blood mononuclear cell , human immunodeficiency virus (hiv) , immunology , genetics , electrical engineering , in vitro , engineering
Four uninfected chimpanzees were each housed in separate cages with an HIV‐infected chimpanzee for six to twenty‐nine months. Despite close daily contact, all uninoculated chimpanzees remained seronegative for HIV, and virus was never isolated from peripheral blood mononuclear cells of the uninfected chimpanzees. These data indicate that the probability of transmission from infected animals to humans is extremely low and also provide supportive evidence for lack of transmission of HIV by casual contact.