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Reference Values for Peripheral Blood Lymphocytes From Aotus lemurinus ssp. griseimembra (Owl Monkey)
Author(s) -
Caldwell Charles W.,
Mrema J.E.K.,
Taylor H.M.,
Green T.J.
Publication year - 1987
Publication title -
journal of medical primatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.31
H-Index - 42
eISSN - 1600-0684
pISSN - 0047-2565
DOI - 10.1111/j.1600-0684.1987.tb00334.x
Subject(s) - biology , monoclonal antibody , cytotoxic t cell , immune system , peripheral blood , immunology , lymphocyte , antigen , t lymphocyte , phenotype , simian , antibody , microbiology and biotechnology , in vitro , gene , genetics
The reactivities of several monoclonal antibodies that define human lymphocyte cell‐surface antigens have been tested with peripheral blood lymphocytes of Aotus lemurinus ssp. griseimembra . Based on reactivity patterns in humans, reactive MoAb were identified that mark pan‐T, helper/inducer, suppressor/cytotoxic, pan‐B, and natural killer cells. Reference values of these subsets in Aotus are presented. These MoAb should provide a useful tool for further phenotypic and functional dissection of the immune system in this simian model of human disease.