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Baboon ( Papio ursinus ) Model to Study Deep Vein Thrombosis Using 111‐Indium‐Labeled Autologous Platelets
Author(s) -
Dormehl Irene C.,
Jacobs D.J.,
Pretorius J.P.,
Maree Marianna,
Franz R.C.
Publication year - 1987
Publication title -
journal of medical primatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.31
H-Index - 42
eISSN - 1600-0684
pISSN - 0047-2565
DOI - 10.1111/j.1600-0684.1987.tb00314.x
Subject(s) - baboon , platelet , thrombosis , deep vein , medicine , vein , pathology , biology
This study evaluates the chacma baboon as a model for investigations on deep vein thrombosis (DVT). There is a good correlation of the baboon and human thrombelastographic parameters (r‐time, k‐time, ma). Investigation on the diagnostic efficacy of 111 In‐labeled platelets as an imaging agent for DVT cast considerable doubt on the procedure, owing to the age of the thrombus.