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Respiration Rate, Heart Rate, and Body Temperature Values in Cynomolgus Monkeys ( Macaca fascicularis ) During Barbiturate Anesthesia
Author(s) -
ZolaMorgan Stuart,
Micheletti Carol
Publication year - 1986
Publication title -
journal of medical primatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.31
H-Index - 42
eISSN - 1600-0684
pISSN - 0047-2565
DOI - 10.1111/j.1600-0684.1986.tb00304.x
Subject(s) - barbiturate , respiration , anesthesia , heart rate , respiration rate , medicine , physiology , blood pressure , anatomy
Respiration rate, heart rate, and body temperature values were obtained from 14 cynomolgus monkeys ( Macaca fascicularis ) during neurosurgery under barbiturate anesthesia. Vital sign values markedly declined below baseline during the early stages of surgery, steadily increased as surgery progressed and neared completion, and finally returned to baseline by the end of the postsurgical recovery period. There was considerable variability among the 14 monkeys, but the ranking of each monkey relative to the others remained constant across the period of observation. The findings suggested that the cynomolgus monkey may be more sensitive to barbiturates than the rhesus monkey, and cynomolgus monkeys may exhibit considerable individual differences in their sensitivity to barbiturates.