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Blood Volume Measurement in Baboons: Simultaneous Estimation of Red Cell Volume and Plasma Volume
Author(s) -
Garner Michael G.,
Phippard Andrew F.,
Horvath John S.,
Duggin Geoffrey G.,
Tiller David J.
Publication year - 1985
Publication title -
journal of medical primatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.31
H-Index - 42
eISSN - 1600-0684
pISSN - 0047-2565
DOI - 10.1111/j.1600-0684.1985.tb00274.x
Subject(s) - plasma volume , volume (thermodynamics) , blood volume , red blood cell , circulatory system , red cell , chemistry , biology , medicine , endocrinology , physics , quantum mechanics
A method is described for frequent sequential blood volume estimation in baboons using 32 P for red cell volume measurements and 125 I‐albumin for simultaneous plasma volume measurements. Values for red cell, plasma, and total blood volumes are reported. Close correlations of the volumes to bodyweight were demonstrated. Circulatory half‐lives of the isotopes, determined from disappearance curves, confirmed their suitability for serial measurements in these baboons.